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Dogs Are First in Polk to Get Stem Cell Therapy for Arthritis

By Robin Williams Adams
THE LEDGER
Published: Sunday, April 10, 2011 at 10:45 p.m.
Last Modified: Sunday, April 10, 2011 at 10:45 p.m.

LAKELAND | Brody and Gracie are medical pioneers in the Polk County veterinary world and they have the shaved patches of fur to prove it.

The two dogs are the first locally to receive stem-cell therapy for arthritis in a procedure allowing the entire process to be done during the same veterinary clinic visit.

"Both of the pets did well," said Dr. Wiliam Latter, the veterinarian at All Creatures Animal Clinic in south Lakeland.

"They seemed to tolerate it well."

Wednesday was a long day for dogs and owners, however, with Brody a bit baffled because this visit to All Creatures didn't result in the doggie massage he's been getting there weekly for his stiffness and pain.

Instead, the 8-year-old Bernese Mountain dog went under anesthesia. X-rays were taken of his hips. Latter and an assistant carried his furry, 125-pound body into a procedure room to extract fat from between his shoulder blades.

"You only need about a tablespoon of fat," said Lynn Marcum, distributor for the Florida branch of MediVet, which sells the stem-cell procedure kit to veterinarians and shows them how to use it.

Although dogs are featured on the company's ads, the procedure also can be used on horses, cats and other animals.

As Brody rested in a large cage, waking up with a dazed look, his fat tissue went to a back room for processing. Previous stem-cell treatments required sending the stem cell-laden fat away to a separate lab to be separated out, Marcum said.

Latter hasn't used earlier stem-cell procedures because of their cost,

the need to send the cells away and insufficient reports on how well it worked. This

one, costing about $1,800 for a dog, is less expensive and he's seeing "a lot of case reports" in which it looks promising for osteoarthritis and dysplasia, abnormal development of tissue.

"They're your own stem cells going back in," Marcum said. "There's no worry about rejection."

Separating the stem cells from the fat, putting them through an enzyme wash, combining them with ­platelet-rich plasma from the animal's own blood and activating both under low-level laser light is the longest part of the procedure.

It can take three or four hours, starting with mincing the fat until it's at the stage of a slushie, before the activated stem cells are ready to be injected into the animal's aching joint.

"It's like a Red Bull for the stem cells," said Kendra Hurrell, who taught the process to Joseph Broussard, a vet tech at All Creatures.

As they separated and prepped the cells, Brody's humans, Alison and Scott Taylor, waited beside their pet

"We just want him to be healthy," Alison Taylor said, explaining that Brody has had dysplasia for five years.

She heard about the procedure on television, researched it and talked to Latter about the procedure.

Waiting along with them was Andrea Nelson, one of Gracie's two owners, who does the massage, water therapy and weight-loss programing for animals at All Creatures.

Gracie, calm throughout the day, went through a process identical to Brody's: remove tissue, separate stem cells, activate them and return to the body.

Gracie, 13, is a Labrador retriever who has arthritis, hip dysplasia and dysplasia of the elbows (where the front legs bend).

Although Nelson and co-owner Donya-Faye Wix give her swimming and other therapies to keep her limber, Nelson said they wanted to try the procedure to reduce her pain.

"You're making the choice because you know they'll feel better, but it's nerve-racking," Nelson said. "We wanted to do everything we could for her."

That included stopping for cheese pizza on the way home from their full day at the veterinary clinic.

Brody was a little sore the day after the procedure, Alison Taylor said, but she added that she could see him putting more weight on his left front leg than he had before the procedure.

Animals may experience an energy boost soon after the procedure. It takes three weeks to four weeks for the stem cells to create restorative growth in the afflicted joints, Marcum said.

"I hope it's successful," Alison Taylor said.

[ Robin Williams Adams can be reached at robin.adams@theledger.com or 863-802-7558. Read her blog at robinsrx.blogs.theledger.com. Follow on Twitter at ledgerROBIN. ]